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The Hidden Immune System Failure Nobody Is Talking About

Host: Kiran Krishnan –
Microbiologist & Leading Microbiome Educator

Co-Host: Jessica Carter
Industry Collaboration Strategist
Most of us were taught the immune system works one of two ways. It fights something off, or it doesn’t. There’s a layer underneath that almost no one talks about. Your frontline immune cells, the ones that respond on contact, can be educated. Researchers call it trained immunity. In this live training, microbiologist Kiran Krishnan walks through what trained immunity is, why most people’s frontline immunity is untrained, where the gut fits in, and the one well-studied natural compound shown to support it. He’s joined by functional medicine dietitian Jessica Carter, who shows how to put the science to work.
What trained immunity actually is, and why the frontline of your immune system was long assumed to have no memory at all
Why most people’s frontline immunity is untrained, firing hard and wide instead of with precision, and what that costs the healthy tissue around it
The direct connection between your gut and your frontline immune cells, and why you can’t address one without the other
How a trained frontline behaves differently: faster, more precise, with far less collateral damage
The one well-studied natural compound, examined at several of the world’s most respected research institutions, shown to support this kind of training at the cellular level
Live Q&A: bring your questions for Kiran and Jessica in real time


About Kiran
Kiran Krishnan is a research microbiologist, educator, and founder of Microbiome Labs. He’s spent over 20 years translating cutting-edge microbiome science into tools, formulations, and strategies used by tens of thousands of practitioners around the world. And now, for the first time, he’s bringing this knowledge straight to you — showing how the microbiome connects to your symptoms and what you can do to support lasting change.

About Jessica
Jessica Carter, MS, RD, CDCES, IFMCP, ERYT-200 is a licensed dietitian, certified functional medicine practitioner, and experienced yoga teacher with over a decade of experience advancing systems-based, personalized care through clinical practice, strategic partnerships, and organizational leadership. As Industry Collaboration Strategist at OvationLab, Jessica helps health and wellness companies translate emerging science into meaningful practitioner engagement, educational initiatives, and adoption strategies rooted in clinical relevance and human-centered implementation. She is recognized for her ability to connect dots across disciplines, oversee large-scale operations, and cultivate strong relationships among partners, teams, and key opinion leaders to drive alignment and impact.